In this webinar, Professor Dan Peer from Tel Aviv University will talk about the application of microfluidics for the preparation of targeted lipid nanoparticles entrapping siRNAs (RNA-tLNPs) directed towards lymphocytes . Special emphasis will be made on the ability to conjugate different ligands and monoclonal antibodies to the surface of LNPs to endow them with targeting capabilities. Examples will focus on T cells and malignant B cells and describe how RNA-tLNPs can be utilized for therapeutic gene silencing in hematological B cell malignancies and as a tool to study leukocyte biology
"Harnessing RNAi Nanomedicine for Manipulating Lymphocyte Function"
Presenter: Prof. Dan Peer
In this webinar, Professor Dan Peer from Tel Aviv University will talk about the application of microfluidics for the preparation of targeted lipid nanoparticles entrapping siRNAs (RNA-tLNPs) directed towards lymphocytes . Special emphasis will be made on the ability to conjugate different ligands and monoclonal antibodies to the surface of LNPs to endow them with targeting capabilities. Examples will focus on T cells and malignant B cells and describe how RNA-tLNPs can be utilized for therapeutic gene silencing in hematological B cell malignancies and as a tool to study leukocyte biology
Thu, Apr 14, 2016 7:30 PM - 9:00 PM CEST
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