Fast and reliable Isolation of Plasma Extracellular Vesicles with the qEV Size Exclusion Chromatography columns

Extracellular vesicles (EVs) are important mediators of intercellular communication and are involved in the transmission of biological information between cells to regulate a broad range of biological processes. EVs contain proteins, mRNA, and miRNA representing the cell they are secreted from and there is increasing evidence that EVs play an important role in normal physiological processes, development, human disease, and viral infections. EVs are found in most biological fluids; plasma is a rich reservoir of vesicles that can be easily obtained by drawing a patient’s blood. However, plasma is also a complex biological sample; rich in protein, high- and low-density lipoproteins (HDL/LDL), salts, ions, nutrients and other particulates and these must be removed before EV analysis. Traditional methods to isolate EVs such as ultracentrifugation and chemical precipitation yield impure aggregated vesicles and are expensive in both time and equipment.1,2 Because of these challenges, there is a need for a rapid, simple, and cost-effective method to isolate EVs from plasma.

qEV Size Exclusion Columns are convenient, available off-the-shelf and quality assured (ISO 13485) so their performance is consistent from column to column. 

Spend your time focusing on your research, versus the isolation of your extracellular vesicles.  Izon Science’s qEV Size Exclusion Columns are the fastest, easiest and most reliable method to isolate extracellular vesicles from cell culture supernatants and complex biological fluids.

For more information check this page: Izon Science's qEV columns

or contact us at info@schaefer-tec.it.